Fig. 4

Distinct genomic profiles associated with CCNE1 expression. Detection of differential somatic mutations in UCEC, including 25% CCNE1^low group (A) and 25% ALKBH5^high group (B). C The CNAs profile analysis about 25% CCNE1^low group and 25% CCNE1.^high group in TCGA dataset by GISTIC2.0. (D-E) Frequency of amplifications and deletions in UCEC with CCNE1 low or high expression (red, amplification, Blue, deletion)