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Fig. 5 | Hereditas

Fig. 5

From: HOXD9/APOC1 axis promotes macrophage M1 polarization to exacerbate diabetic kidney disease progression through activating NF-κB signaling pathway

Fig. 5

Knocking down APOC1 enhances the inhibitory effect of liraglutide on macrophage M1 polarization. (A-B) APOC1 expression levels in NG-treated cells and HG-treated cells were analyzed by qRT-PCR and Western blot. (C-D) APOC1 expression levels in NG-exos and HG-exos were analyzed by qRT-PCR and Western blot. (E-F) The mRNA expressions of iNOS, TNF-α, Arg-1, and CD206. (G) The mRNA expressions analysis of IL-6, NOS2, IL-1β, and MCP-1 by qPCR. The values in the graphs represent the mean ± SD. * P < 0.05; ** P < 0.01, *** P < 0.001

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Hereditas

ISSN: 1601-5223

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