Fig. 2
From: Knockdown of IGF2BP2 overcomes cisplatin-resistance in lung cancer through downregulating Spon2 gene

Deficiency of IGF2BP2 triggered A549 cell apoptosis and cell cycle arrest. A549 cells were transfected with si-IGF2BP2 or oe-IGF2BP2 plasmids. (A) The viability of A549 cells at 0, 24, 48 and 72 h were assessed using the MTT assay. (B) Cell apoptosis and (C) cell cycle distribution of A549 cells were evaluated by flow cytometry. **P < 0.01; ***P < 0.001