Fig. 6
From: Knockdown of IGF2BP2 overcomes cisplatin-resistance in lung cancer through downregulating Spon2 gene
Downregulation of IGF2BP2 reduced the resistance of A549/DDP cells to DDP in vivo.(A) Photographs of animals (upper panel) and xenograft tumors (lower panel). (B) Tumor volume and (C) tumor weight. (D) H&E staining assay was done to observe pathological changes of tumor tissues (scale bar, 50 μm). (E, F) IF staining assay was done to assess CD133 and IGF2BP2 levels in tumor tissues (scale bar, 100 μm). *P < 0.05; **P < 0.01; ***P < 0.001