Fig. 5

Construction of the prognostic signature. (A) C-index values of 101 machine learning algorithms in TCGA-HNSCC and META-HNSCC cohorts; (B) Selection of hub PRGs by the Enet [alpha = 0.1] algorithm; (C) Univariate Cox analysis of hub PRGs in TCGA-HNSCC and META-HNSCC cohorts; (D–E) Survival analysis of different groups in the TCGA-HNSCC and META-HNSCC cohorts