Table 1 Significant MR results of causal associations between gut microbiota and VTE risk

phylum.Firmicutes.id.1672

IVW

14

0.91 (0.86,0.97)

0.002

0.02

0.33

MR Egger

14

0.94 (0.81,1.1)

0.46

0.28

Simple mode

14

0.87 (0.75,1.02)

0.12

Weighted median

14

0.89 (0.83,0.96)

0.004

Weighted mode

14

0.87 (0.76,1)

0.08

MR PRESSO

14

0.91 (0.86,1.01)

0.008

class.Bacilli.id.1673

IVW

18

1.06 (1.01,1.11)

0.02

0.35

0.55

MR Egger

18

0.98 (0.86,1.12)

0.77

0.59

Simple mode

18

1.03 (0.92,1.15)

0.65

Weighted median

18

1.03 (0.97,1.1)

0.37

Weighted mode

18

1.02 (0.93,1.12)

0.67

MR PRESSO

18

1.06 (1.01,0.97)

0.03

order.Actinomycetales.id.420

IVW

5

0.94 (0.88,1)

0.04

0.19

0.86

MR Egger

5

0.99 (0.86,1.14)

0.89

0.87

Simple mode

5

0.94 (0.85,1.04)

0.29

Weighted median

5

0.94 (0.88,1.02)

0.12

Weighted mode

5

0.96 (0.88,1.05)

0.39

MR PRESSO

5

0.94 (0.91,0.97)

0.02

order.Bacillales.id.1674

IVW

9

0.97 (0.94,1)

0.04

0.19

0.86

MR Egger

9

0.89 (0.77,1.03)

0.17

0.91

Simple mode

9

0.99 (0.93,1.06)

0.80

Weighted median

9

0.98 (0.94,1.02)

0.23

Weighted mode

9

0.99 (0.93,1.06)

0.82

MR PRESSO

9

0.97 (0.95,0.98)

0.02

order.Bifidobacteriales.id.432

IVW

14

0.93 (0.87,0.99)

0.02

0.19

0.09

MR Egger

14

0.78 (0.62,0.97)

0.05

0.16

Simple mode

14

0.94 (0.82,1.09)

0.43

Weighted median

14

0.93 (0.87,1.01)

0.07

Weighted mode

14

0.94 (0.79,1.12)

0.50

MR PRESSO

14

0.93 (0.87,0.96)

0.04

order.Lactobacillales.id.1800

IVW

15

1.07 (1.01,1.13)

0.01

0.19

0.51

MR Egger

15

1.02 (0.9,1.17)

0.73

0.47

Simple mode

15

1.02 (0.9,1.15)

0.77

Weighted median

15

1.02 (0.95,1.1)

0.60

Weighted mode

15

1.02 (0.92,1.12)

0.74

MR PRESSO

15

1.07 (1.02,0.98)

0.02

family.Actinomycetaceae.id.421

IVW

5

0.94 (0.88,1)

0.04

0.65

0.86

MR Egger

5

0.99 (0.86,1.14)

0.89

0.87

Simple mode

5

0.94 (0.85,1.05)

0.32

Weighted median

5

0.94 (0.87,1.02)

0.14

Weighted mode

5

0.96 (0.88,1.05)

0.42

MR PRESSO

5

0.94 (0.91,0.97)

0.02

family.Bifidobacteriaceae.id.433

IVW

14

0.93 (0.87,0.99)

0.02

0.65

0.09

MR Egger

14

0.78 (0.62,0.97)

0.05

0.16

Simple mode

14

0.94 (0.82,1.09)

0.44

Weighted median

14

0.93 (0.87,1.01)

0.08

Weighted mode

14

0.94 (0.78,1.13)

0.53

MR PRESSO

14

0.93 (0.87,0.96)

0.04

genus.LachnospiraceaeUCG010.id.11,330

IVW

10

0.93 (0.88,0.99)

0.02

0.95

0.82

MR Egger

10

0.9 (0.78,1.04)

0.20

0.86

Simple mode

10

0.92 (0.82,1.03)

0.18

Weighted median

10

0.93 (0.86,1)

0.04

Weighted mode

10

0.92 (0.82,1.03)

0.17

MR PRESSO

10

0.93 (0.9,1)

0.01

genus.Lactococcus.id.1851

IVW

9

1.04 (1,1.07)

0.04

0.95

0.50

MR Egger

9

1 (0.85,1.16)

0.97

0.58

Simple mode

9

1.07 (0.99,1.15)

0.14

Weighted median

9

1.05 (1,1.1)

0.05

Weighted mode

9

1.06 (0.99,1.15)

0.15

MR PRESSO

9

1.04 (1,0.91)

0.05

genus.Slackia.id.825

IVW

6

0.93 (0.87,0.99)

0.03

0.95

0.13

MR Egger

6

0.81 (0.52,1.26)

0.40

0.16

Simple mode

6

0.98 (0.89,1.09)

0.74

Weighted median

6

0.97 (0.9,1.04)

0.37

Weighted mode

6

0.98 (0.88,1.09)

0.72

MR PRESSO

6

0.93 (0.87,0.88)

0.08