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Fig. 3 | Hereditas

Fig. 3

From: Infiltrating B-cell subtypes and associated hub genes in nasopharyngeal carcinoma identified from integrated single-cell, bulk RNA-sequencing, and immunohistochemical data

Fig. 3

Proportion of different B-cell subtypes and their association with prognosis in NPC. (A-B) Heatmap (A) and boxplot (B) showing the proportion of different B-cell subtypes in bulk RNA-sequencing data. (C-D) Survival curves of switched memory B cells and naïve B cells. ((E) Correlation between the proportion of different B cell subtypes in total cells and different clinical features. (F) Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment of differentially expressed gene in naïve B cells. (G) Immune checkpoint pathway activity of B-cell subtypes. (H) Distribution of immune pathway activity in different B-cell subtypes. (I) The top 10 immune checkpoint pathways significantly enriched in all B-cell subtypes. The node size represents the–log10 p-value. Color intensity is based on the enrichment score

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Hereditas

ISSN: 1601-5223

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