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Fig. 5 | Hereditas

Fig. 5

From: Infiltrating B-cell subtypes and associated hub genes in nasopharyngeal carcinoma identified from integrated single-cell, bulk RNA-sequencing, and immunohistochemical data

Fig. 5

Identification of hub genes. (A, B) Differentially expressed genes (DEGs) between patients with a high and low proportion of infiltrating naïve B cells. The gene symbol is labeled; DEGs were selected according to a p-value < 0.05 and|log2 fold change| > 1. Red represents upregulated gens and green represents downregulated genes. (C) DEGs between the four B-cell subtypes from the single-cell RNA-sequencing dataset. (D) Protein–protein interaction network showing the co-expression patterns of DEGs identified in the bulk-RNA dataset and single-cell RNA-sequencing dataset. The intensity of the color represents the magnitude of the degree of correlation. (E) Subnetwork from the co-expressed genes. (F) Degree of hub genes

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Hereditas

ISSN: 1601-5223

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