Regulation of the Nrf2/HO-1 pathway in chronic obstructive pulmonary disease-induced muscle atrophy using Jinshui Liujian decoction and Bajitian pills: insights from network pharmacology and animal models

Table 1 Comparative analysis of body mass before and after modeling in five groups of mice (g, mean ± SD), COPD model, Western medicine (WM), traditional Chinese medicine (TCM), and TCM-WM combination groups

Group	n	Before Modeling(g)	After Modeling(g)
Control	8	23.21 ± 0.54	26.18 ± 0.33
COPD model	8	22.93 ± 0.58	18.92 ± 0.30
TCM	8	22.63 ± 0.75^*	24.01 ± 0.29^*
WM	8	22.70 ± 0.64^#	24.20 ± 0.37^#
TCM-WM combination^@	8	22.89 ± 0.63^@	24.94 ± 0.39^@
f value		1.12	541.90
P value		0.36	< 0.001

Note: Compared with the control group, P < 0.001 for the four model groups; compared with the model group, P < 0.001 for the other three groups; compared with the WM group (^#), ^*P = 0.27,^@P < 0.001

ISSN: 1601-5223