Table 3 Docking results of hub targets and active ingredient
| Â | Â | Docking affinity score (kcal/mol) | ||
|---|---|---|---|---|
Target | PBD ID | Luteolin | Quercetin | Kaempferol |
AKT1 | 7NH5 | -10.0 | -10.4 | -9.8 |
EGFR | 1M14 | -7.7 | -7.9 | -7.6 |
EP300 | 5LPM | -7.9 | -7.2 | -8.0 |
ESR1 | 1A52 | -9.0 | -9.0 | -7.7 |
HSP90AA1 | 1BYQ | -7.4 | -7.0 | -6.8 |
HSP90AB1 | 3NMQ | -9.0 | -9.1 | -8.8 |
JUN | 1JUN | -5.5 | -5.4 | -5.3 |
SRC | 1A07 | -8.3 | -8.3 | -7.4 |
TP53 | 1A1E | -5.9 | -5.8 | -6.0 |