Fig. 1

GADD45B is downregulated and has diagnostic and prognostic value for SKCM. (A) GADD45B expression in TCGA paracancers and tumors. (B) Low GADD45B levels in SKCM patients in the TCGA database. (C) GADD45B expression by lineage in the CCLE database. (D) GADD45B expression by skin cell line in the CCLE database. (E) GADD45B expression by primary disease in the CCLE database. (F) Lower GADD45B in SKCM than in normal patients according to the HPA database (HPA029816). (G) GADD45B as a diagnostic marker by ROC analysis (AUC, area under the curve). (H) High GADD45B correlated with better prognosis by Kaplan‒Meier curves in SKCM patients