Fig. 8
From: RNA-binding protein gene NOP58 exhibits crucial prognostic and therapeutic value in Ewing sarcoma
Knockdown of NOP58 influenced the apoptosis of EwS cells in vitro and tumor growth in vivo. (A, B, C, D). SK-N-MC and A673 cells were transfected with sh Ctrl, sh1 NOP58 and sh2 NOP58. Cell apoptosis was detected by TUNEL staining assay and flow cytometry. (E, F). Cell cycle distribution was determined by flow cytometry. (G). In vivo tumor growth of mice injected subcutaneously with NOP58-knockdown SK-N-MC cells. * meant p was smaller or equaled 0.05, ** meant p was smaller or equaled 0.01, *** meant p was smaller or equaled 0.001