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  2. Mas-related G protein-coupled receptors (Mrgs) are a subset of GPCRs linked to pain modulation. MrgF was identified as an orphan Mrg whose function and ligand remain unclear. In this study, in addition to its exp...

    Authors: Xuejiao Chen, Yan Chen, Runzhe Shu, Shunyuan Lu, Ming-Min Gu, Chunling Shen, Zhugang Wang and Xiaofang Cui
    Citation: Hereditas 2025 162:31
    Content type: Research Published on:

  3. Nuclear receptor subfamily 2, group F, member 1 (NR2F1) gene variations are associated with Bosch–Boonstra–Schaaf optic atrophy syndrome. The NR2F1 genotype correlates with its phenotype; variants within the DNA-...

    Authors: Juan Liu, Jihong Hu, Pingqiu Zhou, Yaqin Duan and Shuigui Yin
    Citation: Hereditas 2025 162:30
    Content type: Research Published on:

  4. Bladder cancer (BLCA) represents one of the most prevalent urological malignancies worldwide. Bridging integrator 1 (BIN1), a well-characterized tumor suppressor that interacts with and inhibits oncogenic Myc ...

    Authors: Si-yu Chen, Ya-long Zhang, Xiao-ran Li, Ji-rong Wang, Kun-peng Li, Shun Wan, Jian-wei Yang, Hao Wang, Jin-long Cao, Chen-yang Wang, Xin-peng Fan, Sheng-jun Fu, Li-yun Ding, Tuan-jie Che and Li Yang
    Citation: Hereditas 2025 162:29
    Content type: Research Published on:

  5. Non-small cell lung cancer (NSCLC) is a common subtype of lung cancer that has received considerable attention for its potential association with rheumatoid arthritis (RA). However, current understanding of th...

    Authors: Lyubo Wang, Yuxian Dong, Qingcheng Yang, Siyun Liu, Bencheng Wu, Dahang Zhang, Shuai Shen, Chenjun Xin, Zurui Liu, Qiuyang Wu, Guojian Huang and Lincan Duan
    Citation: Hereditas 2025 162:28
    Content type: Research Published on:

  6. Disulfidptosis and ferroptosis are different programmed cell death modes, which are closely related to the development of a variety of diseases, but the relationship between them and ulcerative colitis (UC) is...

    Authors: Yinghao Jiang, Hongyan Meng, Xin Zhang, Jinguang Yang, Chengxin Sun and Xiaoyan Wang
    Citation: Hereditas 2025 162:27
    Content type: Research Published on:

  7. Disulfidptosis, a novel form of metabolism-related regulated cell death, is a promising intervention for cancer therapeutic intervention. Although aberrant expression of long‐chain noncoding RNAs (lncRNAs) exp...

    Authors: Jiangmin Shi, Liang Zhao, Kai Wang, Jieqiong Lin and Jianwei Shen
    Citation: Hereditas 2025 162:26
    Content type: Research Published on:

  10. Rheumatoid arthritis (RA) increases the risk of stroke. However, the relationship between RA and stroke remains unclear. This study aimed to explore the shared genetics architecture (i.e., common genetic basis...

    Authors: Qian Qin, Yong’An Jiang, Hengyi Fan, Raorao Yuan, Bo Zhong, Yichen Zhang, Zile Zhang, Xin Lei, Jianhui Cai and Shiqi Cheng
    Citation: Hereditas 2025 162:23
    Content type: Research Published on:

  11. Research shows that people with multiple sclerosis (MS) are more likely to experience cardiovascular complications. However, the precise mechanisms underlying this association remain unclear. This study invest...

    Authors: Linqin Du, Yangyang Cui, Yang Zhou, Ofe Eugene Kwaku, Xuefeng Ding, Lang Zeng, Shikang Li, Lijuan Xiong, Yonghong Zhang, Peng Zhou, Kun Wang and Rongchuan Yue
    Citation: Hereditas 2025 162:22
    Content type: Research Published on:

  12. Endoplasmic reticulum stress (ERS) and mitochondrial dysfunction (MD) involved in bone metabolism disorders. However, the particular mechanisms of ERS and MD related genes (ERS&MDRGs) in osteoporosis (OP) have...

    Authors: Yuxi Chen, Ke Bi, Chunzhi Zhang, Jiaao Gu, Zhange Yu, Jianping Lu and Lei Yu
    Citation: Hereditas 2025 162:21
    Content type: Research Published on:

  13. Previous research has established a correlation between immune cells and an increased likelihood of Chronic pancreatitis (CP). However, studies investigating the causal relationship remain limited.

    Authors: Chao Zhang, Tao Yang, Yuan Yu, Qian Jia, Wan-Meng Xiao, Sha Liu, Ze-Hui Yu, Cheng-Li Wen, Yan Wei, Hao Li and Mu-Han Lü
    Citation: Hereditas 2025 162:20
    Content type: Research Published on:

  14. The study investigates the role of Cell Division Cycle Associated (CDCA) genes in colorectal cancer (COAD) by analyzing their differential expression, epigenetic alterations, prognostic significance, and funct...

    Authors: Zongquan Zhao, Xinwei Feng, Bo Chen, Yihong Wu, Xiaohong Wang, Zhenyuan Tang, Min Huang and Xiaohua Guo
    Citation: Hereditas 2025 162:19
    Content type: Research Published on:

  16. Immunotherapy has introduced new breakthroughs in improving the survival of head and neck squamous cell carcinoma (HNSCC) patients, yet drug resistance remains a critical challenge. Developing personalized tre...

    Authors: Xiaoqin Luo, Chao Li and Gang Qin
    Citation: Hereditas 2025 162:17
    Content type: Research Published on:

  17. Mitochondrial permeability transition (MPT)-driven necrosis (MPTDN) is a non-apoptotic mode of cell death triggered by oxidative stress and cytosolic Ca2+ overload. Recent evidence suggests that activation of MPT...

    Authors: Zhifei Ma, Wen Chen, Aiping Zhang, Xiaokang Shen and Lin Zheng
    Citation: Hereditas 2025 162:16
    Content type: Research Published on:

  19. Previous observational studies have reported an association between chronic obstructive pulmonary disease (COPD) and osteoporosis (OP). The aim of this study is to investigate the causal relationship between C...

    Authors: Fangjun Yang, Huaming Wang, Miaomiao Liu, Shengtai Pei and Xiaoming Qiu
    Citation: Hereditas 2025 162:14
    Content type: Research Published on:

  23. Ferroptosis has emerged as a promising therapeutic target in cancer treatment. CEP55, a key regulator of cell mitosis, plays a significant role in the tumorigenesis of many malignancies. In this study, we eluc...

    Authors: Sheng Chen, Yangyong Luo, Simin Ruan, Guosen Su and Guoxing Huang
    Citation: Hereditas 2025 162:10
    Content type: Research Published on:

  24. Discs large homolog 2 (DLG2) has been implicated in cancer development, yet its role in cervical cancer remains unclear. This study aims to explore the regulatory mechanism of DLG2 in cervical cancer and its c...

    Authors: Mei Pu, Xia Xiao, Shasha Lv, Daqing Ran, Qian Huang, Mingming Zhou, Qirong Lei, Lingshuang Kong and Qing Zhang
    Citation: Hereditas 2025 162:9
    Content type: Research Published on:

  25. Epidemiological studies have confirmed the relationship between personality trait neuroticism and physical health. However, the relationship between neuroticism and frailty remains unconfirmed. This study empl...

    Authors: Yuhang Xing, Rui Pu, Mengdie Fu, Zhikang Wang, Zhen Wang, Xiaopeng Shang, Guoli Yang and Zhiwei Jiang
    Citation: Hereditas 2025 162:8
    Content type: Research Published on:

  26. Two-sample MR methods were employed to analyze the impact of smoking and bitter beverage consumption on the risk of osteoporosis and osteoporosis with pathological fractures, in order to assess the causal asso...

    Authors: Yanqian Wu, Jianqian Chao, Min Bao, Na Zhang and Leixia Wang
    Citation: Hereditas 2025 162:7
    Content type: Research Published on:

  27. Pancreatic cancer is one of the most malignant abdominal tumors. DDX60 has been shown to be associated with a variety of tumor biological processes. However, DDX60 in pancreatic cancer has not been reported. O...

    Authors: Dongdong Zhang, Enze Zhang, Ying Cai, Yixin sun, Peiji Zeng, Xiaohua Jiang and Yifan Lian
    Citation: Hereditas 2025 162:6
    Content type: Research Published on:

  28. Uterine Corpus Endometrial Carcinoma (UCEC) is a prevalent gynecologic malignancy with complex molecular underpinnings. This study identifies key woundhealing genes involved in UCEC and elucidates their roles ...

    Authors: Fuchuan Jiang, Sajjad Ahmad, Sadia kanwal, Yasir Hameed and Qian Tang
    Citation: Hereditas 2025 162:5
    Content type: Research Published on:

  29. Cervical cancer (CC) is a prevalent gynecological malignancy, contributing to a substantial number of fatalities among women. MicroRNAs (miRNAs) have emerged as promising biomarkers with significant potential ...

    Authors: Yan Zhao, Haitao Chen, Wenhui Zhang, Wei Shang, Jinwei Cao, Huijuan Zhao and Zhixiang Zou
    Citation: Hereditas 2025 162:4
    Content type: Research Published on:

  31. Alzheimer’s disease (AD) is a prevalent neurodegenerative disorder, with antibody-mediated immune responses to infectious diseases agents potentially playing a decisive role in its pathophysiological process. ...

    Authors: Jiayuan Zhang, Mingming Wang, Dong Wang, Linwen Deng and Yao Peng
    Citation: Hereditas 2025 162:2
    Content type: Research Published on:

  35. Cisplatin (DDP) resistance has long posed a challenge in the clinical treatment of lung cancer (LC). Insulin-like growth factor 2 binding protein 2 (IGF2BP2) has been identified as an oncogenic factor in LC, w...

    Authors: Shilei Zhang, Ting Dou, Hong Li, Hongfang Yu, Wei Zhang, Liping Sun, Jingwen Yang, Zhenfei Wang and Hao Yang
    Citation: Hereditas 2024 161:55
    Content type: Research Published on:

  36. Conventional treatments, including surgery, radiotherapy and chemotherapy, have many limitations in the prognosis of glioma patients. Atorvastatin (ATOR) has a significant inhibitory effect on glioma malignanc...

    Authors: Kang Gao, Tao Zhou, YingChun Yin, XiaoJie Sun, HePing Jiang and TangYue Li
    Citation: Hereditas 2024 161:54
    Content type: Research Published on:

  37. Breast cancer is the most prevalent cancer among women worldwide. Most breast cancer-related deaths result from metastasis and drug resistance. Novel therapies are imperative for targeting metastatic and drug-...

    Authors: Valeria Villarreal-García, José Roberto Estupiñan-Jiménez, Vianey Gonzalez-Villasana, Pablo E. Vivas-Mejía, Marienid Flores-Colón, Irma Estefanía Ancira-Moreno, Patricio Adrián Zapata-Morín, Claudia Altamirano-Torres, José Manuel Vázquez-Guillen, Cristina Rodríguez-Padilla, Recep Bayraktar, Mohamed H. Rashed, Cristina Ivan, Gabriel Lopez-Berestein and Diana Reséndez-Pérez
    Citation: Hereditas 2024 161:53
    Content type: Research Published on:

  38. Glioma is a malignancy with challenging clinical treatment and poor prognosis. Platelets are closely associated with tumor growth, propagation, invasion, and angiogenesis. However, the role of platelet-related...

    Authors: Sanlin Wei, Junke Zhou and Bin Dong
    Citation: Hereditas 2024 161:52
    Content type: Research Published on:

  39. Age-related macular degeneration (AMD) is the leading cause of visual impairment in the elderly population. Accumulating evidence has revealed the possible association between metabolites and AMD. This study a...

    Authors: Zhen-Yu Liu, Hang Zhang, Xiu-Li Sun and Jian-Ying Liu
    Citation: Hereditas 2024 161:51
    Content type: Research Published on:

  41. Mitochondria are involved in septic shock and inflammatory response syndrome, which severely affects the life security of patients. It is necessary to recognize and explore the immune-mitochondrial genes in se...

    Authors: Yu-Hui Cui, Chun-Rong Wu, Li-Ou Huang, Dan Xu and Jian-Guo Tang
    Citation: Hereditas 2024 161:49
    Content type: Research Published on:

  42. Platinum-based chemotherapy is one of the main treatments for lung adenocarcinoma (LUAD). However, the toxic side effects and drug resistance of chemotherapeutic drugs on normal cells are still a thorny proble...

    Authors: Lingxue Tang, Yiling Ruan, Beibei Wang, Mingjun Zhang, Jie Xue and Tong Wang
    Citation: Hereditas 2024 161:48
    Content type: Research Published on:

  43. Indole-3-acetic acid (IAA), an indole analog produced by intestinal microorganisms metabolizing tryptophan, has anti-inflammatory and antioxidant properties and thus has potential applications in ovarian prote...

    Authors: Jianxiu Zheng, Liyan Wang, Ahui Liu, Haofei Shen, Bin Wang, Yanbiao Jiang, Panpan Jing, Defeng Guan, Liulin Yu and Xuehong Zhang
    Citation: Hereditas 2024 161:47
    Content type: Research Published on:

  44. Infertility is a global problem being associated with emotional and financial burden. Recent studies have shown contribution of a group of non-coding RNAs, namely circular RNAs (circRNAs) to the etiology of so...

    Authors: Emad Babakhanzadeh, Fakhr-Alsadat Hoseininasab, Ali Khodadadian, Majid Nazari, Reza Hajati and Soudeh Ghafouri-Fard
    Citation: Hereditas 2024 161:46
    Content type: Review Published on:

  45. Gastric cancer (GC) is characterized by its high malignancy and poor prognosis. However, the role of Inhibin subunit beta A (INHBA) in GC remains insufficiently understood. This study aims to comprehensively e...

    Authors: Xueying Li, Haizhong Jiang, Yangbo Fu, Qiying Hu, Xianlei Cai and Guoqiang Xu
    Citation: Hereditas 2024 161:45
    Content type: Research Published on:

  46. Stage 4 neuroblastoma (NBL), a solid tumor of childhood, has a poor prognosis. Despite intensive molecular genetic studies, no targetable gene abnormalities have been identified. Stage 4S NBL has a characteris...

    Authors: Fumihiko Nakamura, Yushi Nakano and Shiro Yamada
    Citation: Hereditas 2024 161:44
    Content type: Research Published on:

  47. The role of vitamin C as an antioxidant in guarding against osteoporosis in adults is still debated. This research employs both a cross-sectional study and a two-sample bidirectional Mendelian randomization (M...

    Authors: Zhiwen Liu, Zijing Peng, Yelin Zhong, Jianjun Wu, Sicheng Xiong, Wei Zhong, Jiehua Luo, Zhihai Zhang and Hongxing Huang
    Citation: Hereditas 2024 161:43
    Content type: Research Published on:

  48. Low back pain (LBP) and insomnia are common global health issues, but their relationship and potential mediators remain unclear. This study aimed to explore the impact of insomnia on LBP using mendelian random...

    Authors: WeiSong Lu, YongQuan Wang, Yue An, MengZe Li, Sen Wang, Jie Lian and Hegui Xu
    Citation: Hereditas 2024 161:42
    Content type: Research Published on:

  49. Lung adenocarcinoma (LUAD) is the most common lung cancer subtype, and the prognosis of affected patients is generally poor. The traditional Chinese medicine Uncaria rhychophaylla has been reported to exhibit ant...

    Authors: Liping Chen, Jing Xing, Jiapei Lv, Sainv Si, Huaying Wang and Wanjun Yu
    Citation: Hereditas 2024 161:41
    Content type: Research Published on:

  50. Diabetic kidney disease (DKD) is a complication caused by end-stage diabetes mellitus and usually results in glomerular podocyte injury. Exosomes are important for intercellular information exchange. However, ...

    Authors: Ya Feng, Yalan Zhang, Fang Gao, Miaomiao Liu and Yangyan Luo
    Citation: Hereditas 2024 161:40
    Content type: Research Published on:
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Hereditas

ISSN: 1601-5223

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